boschmain

Ace Inhibitor

Antihistamine

Antiplatelet

Antivival

Aminoglycosides

Beta Blocker

Calcium Antagonist

Cephalosporin

Coenzyme

Diaminopyvimidine

Loop Diuretic

Glucocorticoid

H2 Blocker

Haemostatic/
Fibronolytic

Lincosmide

Macrodile

Penicillin

Phenylacetic acid

Proton Pump Inhibitor

Statin

Quinolones

Untitled Document

Glax
(Gatifloxacin)

200mg & 400mg Coated Tablets, 200mg/100ml & 400mg/40ml I.V. infusion
Gatifloxacin a new 4th generation 8-methoxy fluroqunolone.
The treatment of a wide variety of infections.

stands out vis the currently available quinolones.

Clinically Potent
Much lover MIC90 (Ug/ml)
Gram+ve
S.aureus	0.03-0.12
S.pyogenes	0.25-0.5
S.pneumoniae	0.5-1

Gram-ve
E.coli	0.008-0.06
K.pneumoniae	0.03-0.5
Salmonella spp.	0.008-0.12
Shiegella spp.	0.002-0.03
H.influenzae	<0.008-0.03
M.catarrhalis	0.06-0.12

Atypocal
Chlamydia spp.	0.5-2
Legionella spp	0.008-0.06
Mycoplasma spp	0.06-0.13
H.pylori	0.03-0.06
B.fragilis	0.25-4

93%	91.1%
Cure Rate	Eradication

Pharmacokinetic
Rapid onset of action	-within 1 hour
Excellent bioavailability	-.96%
Serum Protein Binding	-Just 20% (Concentration independent)
No Drug Interaction.
Decrease rate of resistance development
The mean elimination half life	-7-14 hours,
independent of dose and route of administration.

Uncomplicated
Gonorrhea

Study Design.
Double-blind,randomized controlled trial

Patient Group:
Men340,Women388(16years old or older)

Dosage:
Gatifloxacin(400mg or 600mg)Dingle Dose

Once Daily FDA Approved Glaz Dosage Potent & Safe
Infection	Daily Dose	Duration
Acute Bacterial Sinusitis	400 mg	10 Days
Acute Bacterial Exacerbation Of Chronic Bronchitis(AECB)	400 mg	7-10 days
Community Acquired Penumonia (CAP)	400 mg	7-14 Days
Uncomplicated Urinary Tract infections(Cystitis)	400 mg	Single Dose
Uncomplicated Urinary Tract infections(Cystitis)	200 mg	3 Days
Complicated Urinary Tract Infections	400 mg	7-10 Days
Uncomplicated Urethral Gonorrhea In Men	400 mg- 600mg	Single Dose
Endocervical And Rectal Gonorrhea In Women	400 mg- 600mg	Single Dose
Acute Pyelonephritis	400 mg	7-10 Days